R21 phase: 2/1/2016 – 1/31/2017 R33 phase: 2/1/2017 – 7/31/2020 Red blood cell microparticles (RMPs) to reduce bleeding following hemorrhagic stroke. NIH/NINDS (R33 phase will depend on results of R21 phase) R21NS094896 (IGNITE mechanism) Dr. Dave (PI) The major goal of this project is to lower hematoma growth following intracerebral hemorrhage using RMPs.
08/01/2019-07/30/2022 Florida Department of HeathDr. Dave, (Principal Investigator) Nicotine exposure and intracerebral hemorrhage. These proposed studies will test efficacy of red blood cell microparticles (RMP) to limit hematoma expansion in a clinically relevant animal model of spontaneous intracerebral hemorrhage.